The significant rise in antibiotic-resistant infections among children calls for urgent global health action and a reassessment of antibiotic usage.
Child Deaths from Antibiotic Resistance Reach Alarming Levels

Child Deaths from Antibiotic Resistance Reach Alarming Levels
A new study reveals that over three million children died in 2022 due to infections resistant to antibiotics, predominantly in Africa and South East Asia.
In a startling revelation, a recent study has estimated that more than three million children worldwide succumbed to antibiotic-resistant infections in 2022. The devastating impacts were primarily seen in Africa and South East Asia, regions identified as the most vulnerable. This alarming trend, attributed to antimicrobial resistance (AMR), poses one of the most pressing public health challenges today.
AMR arises when infectious microbes evolve and become immune to standard antibiotic treatments, resulting in dire consequences for affected populations. The study, led by Dr. Yanhong Jessika Hu of the Murdoch Children's Research Institute and Professor Herb Harwell from the Clinton Health Access Initiative, utilized data from various reputable sources, including the World Health Organization (WHO) and the World Bank. According to their findings, AMR-related child deaths increased by over ten times just within the last three years, exacerbated by the pandemic's impact on healthcare practices.
The role of antibiotics in treating bacterial infections is critical; they are widely prescribed for various ailments, from minor skin infections to serious cases like pneumonia. However, their efficacy is being threatened as misuse and over-prescription lead to drug resistance. Alarmingly, there has been a reported 160% increase in the use of "watch antibiotics" in South East Asia during the years 2019 to 2021 and a 126% increase in Africa. Likewise, "reserve antibiotics," which serve as last-resort options, saw a 125% increase in Africa over the same timeframe.
This trend poses a dire warning of reduced treatment alternatives for dangerous multi-drug-resistant infections, prompting concerns from health experts. Professor Harwell emphasized the urgent need for global focus, stating, “AMR affects everyone, but especially children,” as he prepares to present the findings at the upcoming Congress of the European Society of Clinical Microbiology and Infectious Diseases in Vienna.
The WHO categorizes AMR as one of the most critical health threats globally. A multifaceted crisis influenced by medical practices, environmental factors, and cultural habits, finding a definitive solution remains complex. Harwell emphasizes that proactive measures—like improving immunization and water sanitation—are crucial in preventing infections from arising.
Dr. Lindsey Edwards from King’s College London remarked that these findings should awaken global health leaders to the urgent actions needed to avert a potential regression in child health advancements. The current trajectory suggests that without decisive intervention, the progress made over decades in child health could be severely compromised.