**Tribute to a Hero: Australian Blood Donor James Harrison Passes Away at 88**

Wed Mar 12 2025 21:22:49 GMT+0200 (Eastern European Standard Time)
**Tribute to a Hero: Australian Blood Donor James Harrison Passes Away at 88**

One of the world’s most renowned blood donors, whose plasma saved millions of lives, has passed away.


James Harrison's remarkable legacy as a lifesaver through his blood donations will forever be remembered.

With a profound impact on countless lives, James Harrison, affectionately known as the "man with the golden arm," has left the world at the age of 88. He passed away in his sleep at a nursing home in New South Wales, Australia, as reported by his family on February 17. Harrison's blood, rich with a rare antibody known as Anti-D, has played a crucial role in saving the lives of over 2 million babies by preventing severe blood disorders in newborns.

His journey as a blood donor began at the young age of 18 after he himself received transfusions during a life-threatening chest surgery at 14. Fueled by gratitude, Harrison made it a point to donate plasma every two weeks until he was 81. His dedication earned him a world record for the most blood plasma donated in 2005—a title he held until 2022.

Harrison's daughter, Tracey Mellowship, expressed how proud her father felt for the many lives he saved, stating, "He always believed it does not hurt, and the life you save could be your own." Harrison's connection to anti-D immunization ran deeper, as family members, including Mellowship and his grandchildren, benefited from the preventive treatment.

The significance of Anti-D injections is critical, protecting unborn babies from hemolytic disease of the fetus and newborn (HDFN). Prior to the development of such treatments in the mid-1960s, the mortality rate for diagnosed infants was exceedingly high. Harrison's remarkable blood properties may have stemmed from his extensive transfusions as a teenager.

Today, fewer than 200 donors capable of producing Anti-D are active in Australia, yet they are essential in supporting approximately 45,000 mothers annually. Lifeblood, Australia’s Red Cross Blood Service, is actively collaborating with the Walter and Eliza Hall Institute of Medical Research to cultivate lab-grown anti-D antibodies, aiming to expand this vital resource for pregnant women worldwide. Their research director, David Irving, regards this initiative as a long-sought goal in medical science, emphasizing the need for committed donors who can consistently provide high-quality antibodies.

James Harrison's extraordinary legacy symbolizes hope and resilience, leaving an indelible mark on the lives of families and the healthcare community. His selfless actions will forever be honored and remembered as a testament to the power of one individual’s generous spirit.

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